Search on: CRUSH SYNDROME 
Descriptors Found: 1
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Descriptor English:   Crush Syndrome 
Descriptor Spanish:   Síndrome de Aplastamiento 
Descriptor Portuguese:   Síndrome de Esmagamento 
Tree Number:   C26.797.240
Definition English:   Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia. 
See Related English:   Compartment Syndromes
 
History Note English:   91(75); was see under SHOCK, TRAUMATIC 1979-90; was see under KIDNEY FAILURE, ACUTE 1967-78; was see under ACUTE RENAL FAILURE 1963-66 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   3461 
Unique Identifier:   D003444 

Occurrence in VHL:
 

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